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Tips for parents to identify children with vision problems

January 13, 2016

Subsequently, 10 healthy volunteers were enrolled in a controlled feeding experiment in which their diets were fixed for a 10-day period. All ten subjects in the controlled-feeding experiment were in the Bacteroides group at the start, during, and at the end of the experiment. Their gut microbiomes changed within one day but stayed within the same broad Bacteroides group, even if they ate a diet high in carbohydrates over the 10-day period, emphasizing the short-term stability of the enterotypes.

There are several potential applications of this research. The Penn investigators are currently exploring the relationship between dietary therapies for Crohn's and the composition of the gut microbiome.

"Crohn's disease is caused in part by the way our body responds to the microbes in our intestines," explains Lewis. "Dietary therapies are different from most other Crohn's disease therapies because the dietary therapies don't suppress the immune system. One hypothesis is that these dietary therapies work by changing what organisms live in the intestines."

Roughly 1.5 million people in the United States suffer from ulcerative colitis or Crohn's disease, whose symptoms include abdominal pain, bleeding, nausea, and diarrhea.

The next line of study will be to identify changes in microbial composition associated with successful dietary intervention for these diseases , then optimize ways of creating these changes for improved therapy.

Source: University of Pennsylvania School of Medicine